منابع مشابه
Reproductive toxicology. Tris(2-chloroethyl)phosphate.
Background: Bcl-3 as an oncoprotein is overexpressed in nasopharyngeal carcinoma (NPC). Nedd4 binding protein 2 (N4BP2), which is located in the NPC susceptibility locus, is a Bcl-3 binding protein. This study is aimed to explore the association between N4BP2 genetic polymorphism and the risk of NPC. Methods: We performed a hospital-based case-control study, including 531 sporadic NPC and 480 c...
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Titanate nanoscrolls, a recently discovered variant of TiO2 nanocrystals, are tested as reactive sorbent for chemical warfare agent (CWA) decontamination. The large surface area of the uncapped tubules provides the desired rapid absorption of the contaminant while water molecules, intrinsic constituents of titanate nanoscrolls, provide the necessary chemistry for hydrolytic reaction. In this st...
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A bioassay of (2-chloroethyl)trimethylammonium chloride for possible carcinogenicity was conducted by administering the test chemical in feed to F344 rats and B6C3F1 mice. Groups of 50 rats of each sex were administered either 1,500 or 3,000 ppm of the compound for 108 weeks, and 50 mice of each sex were administered 500 or 2,000 ppm for 102 weeks. Matched controls consisted of 20 untreated and...
متن کاملSensitivity of human and murine hematopoietic precursor cells to 2-[3-(2-chloroethyl)-3-nitrosoureido]-D-glucopyranose and 1,3-bis(2-chloroethyl)-1-nitrosourea.
The sensitivity of mouse and human bone marrow hematopoietic precursor cells [colony-forming units committed to granulocyte-macrophage differentiatin (CFU-C)] was determined after in vitro incubation with chlorozotocin (2-[3-(2-chloroethyl)-3-nitrosoureido]-D-glucopyranose), or 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU), with the use of drug concentrations achieved during clinical administrati...
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ژورنال
عنوان ژورنال: Canadian Journal of Chemistry
سال: 1955
ISSN: 0008-4042,1480-3291
DOI: 10.1139/v55-001